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Primary skin keratinocytes A and B. or the primary skin fibroblasts C and D. were pretreated with gremlin (25 ng/mL) for 30 min, cells were subjected to UV (20 mJ/cm2) radiation and then cultured in complete medium for indicated time, ROS production (A and C) and DNA single strand breaks (SSBs) (B and D) were tested by listed assays. *P < 0.05 vs. “C” group. #P < 0.05 vs. UV only group.
