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. 2016 Nov 4;7(51):84999–85020. doi: 10.18632/oncotarget.13113

Figure 11. Prediction model of the structural alterations in K128_R130del PTEN mutant.

Figure 11

A. Superimposition of WT (in blue) and K128_R130del (in yellow) PTEN molecules (only the phosphatase domain is shown) performed by Swiss-Model. In red is indicated the tract of alpha helix missing in the PTEN mutant. B. Changing in amino acidic bonds between WT and PTEN K128_R130 PTEN in the phosphatase domain. In red is indicated the tract of alpha helix lost in the deleted mutant. The green lines indicate the hydrogen bonds. The analysis was perfomed by Swiss-Model.