Table 1. Summary of the main mutations in the PI3K-Akt pathway and p53, up to now reported in cell lines used in this study (Cosmic v75, http://cancer.sanger.ac.uk/cosmic).
Cell line | PI3KCI | PTEN | Akt | P53 |
---|---|---|---|---|
OAW42 | H1047L | WT | WT | WT |
OVCAR 3 | WT | WT ? | WT | R248Q |
A2780 | E365K | K128_R130del | WT | WT |
SKOV-3 | H1047R | WT | WT | Null |