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. 2004 Dec 2;32(21):6367–6377. doi: 10.1093/nar/gkh963

Figure 3.

Figure 3

Mutation spectra for cst alleles of cdc27 and pol3. (A) Nucleotide sequence of a 450 bp region of cdc27+ genomic DNA (from nucleotide 681–1130, where the ATG is at 1) showing the molecular structure of the cdc27 cst alleles. Six different mutation types are indicated, as follows: found in R39 allele (22 bp duplication of region bounded by GACA repeats underlined in pink), R3 and three isoalleles (16 bp duplication, GACA repeats, green), R25 and one isoallele (121bp, ACAATCG, red), R40 allele (58 bp, AGAAG, blue), R5 allele (173 bp, AAAT, orange) and R6 and seven isoalleles (insertion of single C in CCCCCC sequence, indicated by yellow bar). (B) Nucleotide sequence of an 80 bp region of pol3+ genomic DNA (from nucleotide 2906–2985, where the ATG is at 1) showing the molecular structure of the pol3 cst alleles. Two different mutants were obtained: R37 (27 bp duplication of region bounded by TGGTGA repeats underlined in orange), and R18 (C to T mutation, causing H969 to be mutated to Y969).