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. 2016 Nov 8;7(51):85063–85078. doi: 10.18632/oncotarget.13195

Figure 2. PIK3R2 depletion reduces PI3K pathway activity in CaLu-1 and H226 lung SQCC cell lines.

Figure 2

CaLu-1 or H226 cells expressing inducible PIK3R2 shRNA were cultured alone or with doxycycline (2 μg/ml, 72 h); extracts were examined in WB. Mr indicates relative mobility. Graphs show the percent of maximal S472-pAkt, T308-pAkt and T389-pp70S6K signal, normalized to Akt or p70S6K and compared to the control cell signal at 30 min post-stimulation, considered 100%. * P<0.05; ** P<0.01; Student's t test.