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. 2016 Nov 8;7(51):85079–85096. doi: 10.18632/oncotarget.13196

Table 1. Correlations between IL-37 Expression level and clinicopathological variables of 101 cases of HCC.

Clinicopathological variables Number of each group IL-37 expression p value
high low
All cases 101 50 51
Age (years) 0.549
 <50 44 20 24
 ≥50 57 30 27
Gender 0.842
 Male 55 28 27
 Female 46 22 24
Tumor size(cm) 0.046
 <5 44 27 17
 ≥5 57 23 34
Histological differentiation 0.112
 Well 39 18 21
 Moderate 30 19 11
 Poor 32 13 19
Liver cirrhosis 0.216
 Absence 36 21 15
 Presence 65 29 36
Serum AFP (ug/ml) 0.836
 ≤400 35 18 17
 >400 66 32 34
BCLC stage 0.030
 A 18 13 5
 B 36 19 17
 C 47 18 29
HBV 1.000
 Negative 11 5 6
 Positive 90 45 45
Microvascular invasion 0.046
 Yes 47 18 29
 No 54 32 22

AFP, α-fetoprotein; BCLC stage, Barcelona Clinic Liver Cancer stage; HBV, hepatitis B virus;