Table 1. Correlations between IL-37 Expression level and clinicopathological variables of 101 cases of HCC.
| Clinicopathological variables | Number of each group | IL-37 expression | p value | |
|---|---|---|---|---|
| high | low | |||
| All cases | 101 | 50 | 51 | |
| Age (years) | 0.549 | |||
| <50 | 44 | 20 | 24 | |
| ≥50 | 57 | 30 | 27 | |
| Gender | 0.842 | |||
| Male | 55 | 28 | 27 | |
| Female | 46 | 22 | 24 | |
| Tumor size(cm) | 0.046 | |||
| <5 | 44 | 27 | 17 | |
| ≥5 | 57 | 23 | 34 | |
| Histological differentiation | 0.112 | |||
| Well | 39 | 18 | 21 | |
| Moderate | 30 | 19 | 11 | |
| Poor | 32 | 13 | 19 | |
| Liver cirrhosis | 0.216 | |||
| Absence | 36 | 21 | 15 | |
| Presence | 65 | 29 | 36 | |
| Serum AFP (ug/ml) | 0.836 | |||
| ≤400 | 35 | 18 | 17 | |
| >400 | 66 | 32 | 34 | |
| BCLC stage | 0.030 | |||
| A | 18 | 13 | 5 | |
| B | 36 | 19 | 17 | |
| C | 47 | 18 | 29 | |
| HBV | 1.000 | |||
| Negative | 11 | 5 | 6 | |
| Positive | 90 | 45 | 45 | |
| Microvascular invasion | 0.046 | |||
| Yes | 47 | 18 | 29 | |
| No | 54 | 32 | 22 | |
AFP, α-fetoprotein; BCLC stage, Barcelona Clinic Liver Cancer stage; HBV, hepatitis B virus;