Table 3. The expression levels of DDX60 and disease-specific and recurrence-free survival for patients of oral SCC and three primary subsites.
| DDX60 (50th percentile) | No. (%) | Disease-specific survival | Recurrence-free survival | |||
|---|---|---|---|---|---|---|
| AHR (95% CI) | p-value* | AHR (95% CI) | p-value* | |||
| Buccal mucosal SCC | Low (0-4) | 92 (51.1) | 1.00 | 1.00 | ||
| High (5-7) | 88 (48.9) | 0.90 (0.57-1.42) | 0.638 | 0.90 (0.57-1.42) | 0.638 | |
| Tongue SCC | Low (0-4) | 145 (60.2) | 1.00 | 1.00 | ||
| High (5-7) | 96 (39.8) | 1.04 (0.70-1.54) | 0.844 | 1.57 (1.05-2.35) | 0.027 | |
| Lip SCC | Low (0-4) | 41 (56.2) | 1.00 | 1.00 | ||
| High (5-7) | 32 (43.8) | 5.13 (1.32-19.90) | 0.018 | 2.58 (0.98-6.83) | 0.056 | |
| Total: Oral SCC | Low (0-4) | 278 (56.3) | 1.00 | 1.00 | ||
| High (5-7) | 216 (43.7) | 1.07 (0.80-1.42) | 0.649 | 1.36 (1.02-1.81) | 0.034 | |
Abbreviations: SCC, squamous cell carcinoma; CHR, crude hazard ratio; CI, confidence interval; AHR, adjusted hazard ratio.
*
p-value were adjusted for cell differentiation (moderate + poor vs. well) and AJCC pathological stage (stage III+IV vs. stage I+II) by multiple Cox‘s regression.
Bold values denote statistically significant.