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. 2016 Nov 16;7(51):85464–85471. doi: 10.18632/oncotarget.13399

Table 3. The associations between genetic polymorphisms and clinical characteristics of T2D.

SNP genotype n HbA1c TG Cr Cys-c BMI
mean ± SD p* mean ± SD p* mean ± SD p* mean ± SD p* mean ± SD p*
rs2811893(MYSM1) TT 130 9.56±2.81 0.083 2.53±2.20 0.906 71.18±38.63 0.006* 0.87±0.26 0.975 24.79±3.59 0.495
CT 148 9.15±1.98 2.51±2.19 61.95±18.39 0.87±0.56 24.90±3.36
CC 40 8.68±1.66 2.68±2.37 11.93±1.89 0.86±0.17 25.52±3.24
rs13064954(Unknown) AA 4 10.95±2.03 0.343 7.59±5.17 0.001* 66.47±21.70 0.584 0.85±0.20 0.615 25.27±3.94 0.555
GG 257 9.22±2.40 2.53±2.20 64.67±27.78 0.85±0.23 24.82±3.52
AG 58 9.25±1.99 2.22±1.51 68.94±31.10 0.97±0.84 25.35±3.06
rs17376456(KIAA0825) AA 280 9.35±2.38 0.039* 2.56±2.91 0.6 65.56±29.67 0.88 0.87±0.44 0.526 24.92±3.49 0.884
GA 39 8.53±1.78 2.36±1.49 64.83±15.70 0.83±0.20 25.00±3.44
rs7772697(Unknown) TT 223 9.18±2.40 0.455 2.61±2.38 0.584 65.88±29.90 0.916 0.88±0.48 0.779 25.25±3.48 0.028*
CT 85 9.51±2.26 2.39±1.83 64.48±25.11 0.85±0.19 24.09±3.34
CC 11 8.85±1.23 2.08±0.90 63.29±18.46 0.83±0.30 24.69±2.28
rs3918227(NOS3) CA 49 8.96±1.74 0.338 2.00±1.07 0.117 63.85±18.03 0.664 1.02±0.91 0.045* 25.09±3.53 0.075
CC 270 9.31±2.42 2.63±2.35 65.76±29.82 0.84±0.23 24.89±3.43
rs4838605(ARHGAP22) TT 243 9.34±2.43 0.216 2.66±2.36 0.041* 65.77±23.91 0.737 0.89±0.46 0.168 24.95±3.28 0.777
TC 76 8.97±1.97 2.13±1.56 64.51±39.42 0.81±0.25 24.82±3.92
rs6214(IGF1) TT 72 10.10±3.34 0.006* 2.51±2.36 0.155 61.03±15.20 0.319 0.85±0.27 0.571 25.10±3.43 0.803
CC 105 8.98±1.86 2.22±1.60 66.57±26.55 0.90±0.63 24.76±3.51
TC 142 9.03±1.91 2.78±2.48 66.90±34.05 0.85±0.26 24.96±3.41

HbA1C = glycosylated hemoglobin A1c; TG = triglyceride; Cr = creatinine; Cys-c = cystatin C; BMI= body mass index;

OR = odds ratio; 95%CI = 95 % confidence interval;

*p ≤ 0.05 indicates statistical significance.