Table 1. Relationship between the expression of eIF4E, VEGF-C, E-cadherin and MMP-2 as well as clinical pathological parameters.
Pathological parameters | n | eIF4E positive | VEGF-C positive | E-cadherin positive | MMP-2 positive | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | X2 | P | n | X2 | P | n | X2 | P | n | X2 | P | ||
Age (year) | |||||||||||||
< 50 | 28 | 24 | 1.299 | 0.254 | 21 | 0.017 | 0.894 | 16 | 0.434 | 0.515 | 23 | 0.799 | 0.371 |
≥50 | 80 | 75 | 61 | 40 | 59 | ||||||||
Sex | |||||||||||||
Male | 70 | 66 | 1.786 | 0.181 | 55 | 0.762 | 0.382 | 33 | 1.767 | 0.184 | 50 | 2.201 | 0.138 |
Female | 38 | 33 | 27 | 23 | 32 | ||||||||
Tumor Differentiation | |||||||||||||
Low | 45 | 39 | 2.552 | 0.112 | 35 | 0.145 | 0.704 | 12 | 17.33 | < 0.01 | 37 | 1.673 | 0.196 |
Moderate, High | 63 | 60 | 47 | 44 | 45 | ||||||||
The Depth of Invasion | |||||||||||||
In serosa | 35 | 30 | 2.402 | 0.121 | 19 | 13.27 | <0.01 | 23 | 3.986 | 0.046 | 22 | 4.838 | 0.028 |
Outside of serosa | 73 | 69 | 63 | 33 | 60 | ||||||||
Lymph Node Metastasis | |||||||||||||
Yes | 82 | 80 | 15.49 | <0.01 | 70 | 16.61 | <0.01 | 35 | 10.183 | <0.01 | 68 | 9.133 | <0.01 |
No | 26 | 19 | 12 | 31 | 14 | ||||||||
Tumor Stage | |||||||||||||
A+B | 26 | 19 | 15.49 | <0.01 | 9 | 31.97 | <0.01 | 29 | 9.857 | <0.01 | 15 | 6.229 | 0.013 |
C+D | 82 | 80 | 73 | 27 | 67 |