Table 1. Relationship between the expression of eIF4E, VEGF-C, E-cadherin and MMP-2 as well as clinical pathological parameters.

Pathological parameters	n	eIF4E positive			VEGF-C positive			E-cadherin positive			MMP-2 positive
		n	X2	P	n	X2	P	n	X2	P	n	X2	P
Age (year)
< 50	28	24	1.299	0.254	21	0.017	0.894	16	0.434	0.515	23	0.799	0.371
≥50	80	75			61			40			59
Sex
Male	70	66	1.786	0.181	55	0.762	0.382	33	1.767	0.184	50	2.201	0.138
Female	38			33	27			23			32
Tumor Differentiation
Low	45	39	2.552	0.112	35	0.145	0.704	12	17.33	< 0.01	37	1.673	0.196
Moderate, High	63	60			47			44			45
The Depth of Invasion
In serosa	35	30	2.402	0.121	19	13.27	<0.01	23	3.986	0.046	22	4.838	0.028
Outside of serosa	73	69			63			33			60
Lymph Node Metastasis
Yes	82	80	15.49	<0.01	70	16.61	<0.01	35	10.183	<0.01	68	9.133	<0.01
No	26	19			12			31			14
Tumor Stage
A+B	26	19	15.49	<0.01	9	31.97	<0.01	29	9.857	<0.01	15	6.229	0.013
C+D	82	80			73			27			67