Table 1. Cytotoxicity of TPL, araC ADM against drug-naïve NALM-6 cells and their chemoresistant NALM-6/R counterparts.
Agents | IC50 (μM) | Fold increase | P value | |
---|---|---|---|---|
NALM-6 | NALM-6/R | |||
TPL | 0.035 ± 0.003 | 0.032 ± 0.004 | 0.91 | > 0.05 |
araC | 0.15 ± 0.07 | 115.00 ± 23.12 | 766.67 | < 0.01 |
ADM | 0.11 ± 0.03 | 4.82 ± 0.97 | 43.82 | < 0.01 |
Note: Cytotoxicity was assessed using the CCK-8 assay.