Table 2. TPL-enhanced cytotoxicity of araC or ADM in NALM-6/R cells.
Agents | IC50 (μM) | Fold decrease | P value |
---|---|---|---|
AraC | 45 ± 3.27 | − | < 0.01 |
AraC (+ TPL*) | 2.25 ± 0.72 | 20.00 | |
ADM | 4.85 ± 0.95 | − | < 0.01 |
ADM (+ TPL*) | 0.32 ± 0.081 | 15.16 |
Note: Cytotoxicity was assessed using the CCK-8 assay. * TPL = 10 nM (IC20 concentration).