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. 2016 Dec 2;8(2):2083–2095. doi: 10.18632/oncotarget.13781

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Copyright: © 2017 Rogers et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Examples of inhibitors in clinical development which target various nodes of the PI3K signalling pathway, including class I PI3K (pan or isoform), AKT and mTOR. Specific targets are given in brackets.