Figure 1. The major steps of the emergence of precision medicine.

Precision medicine experienced five important steps from 1985 to 2015. HGP leads us to enter the genomic era in 1985. With the explosive development of biomedical technology, the second and next generation sequencing technology was invented in the 2000s, making gene sequencing much faster, cheaper and preciser. Big data and translational medicne promoted the development of precision medicine. A framework of the “toward presision medicine” established a conception of new therapeutic strategy in 2011. Precison medicion was presented officially by President Obama in 2015.