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. 2016 Dec 4;8(2):2141–2152. doi: 10.18632/oncotarget.13798

Figure 2. Precision medicine used for the treatment of HNSCC.

Figure 2

This figure shows 5 major methods of precision medicine used in HNSCC patient: (1) inhibitors targeting cell surface signaling receptors, including EGFR, VEGFR, HER2 (2) inhibitors targeting cellular signaling pathways, including PI3K/Akt/mTOR, RAS/RAF/MEK/ERK, JAK/STAT3 (3) precision genetic manipulation therapies, including gene disruption therapy, gene addition therapy and epigenetic modification therapy (4) precision medicine combining with surgery (5) precision targeted radionuclide therapy.