Table 3. Meta-analysis of association between increased NEAT1 expression and clinicopathological parameters.
| Clinicopathological parameters | Studies (n) | Patients (n) | OR (95% CI) | P-value | Heterogeneity | ||
|---|---|---|---|---|---|---|---|
| I2(%) | Ph | Model | |||||
| Age (≥ 55 vs. < 55 years) | 7 | 945 | 0.95 (0.73–1.25) | 0.74 | 0 | 0.65 | Fixed |
| Gender (Male vs. Female) | 6 | 796 | 0.96 (0.72–1.28) | 0.77 | 40 | 0.14 | Fixed |
| Smoking (Yes vs. No) | 2 | 227 | 0.96 (0.54–1.71) | 0.9 | 0 | 0.61 | Fixed |
| Tumor size (≥ 5 cm vs. <5 cm) | 5 | 677 | 1.74 (1.26–2.41) | < 0.001 | 0 | 0.41 | Fixed |
| Lymph node metastasis (Yes vs. No) | 6 | 806 | 2.29 (1.71–3.06) | < 0.001 | 18 | 0.3 | Fixed |
| TNM stage (III–IV vs. I–II) | 7 | 945 | 3.60 (2.27–5.72) | < 0.001 | 58 | 0.03 | Random |
| Tumor differentiation (Poor vs. Moderate/Well) | 5 | 334 | 2.16 (1.58–2.93) | < 0.001 | 0 | 0.77 | Fixed |
| Distant metastasis (Yes vs. No) | 5 | 755 | 3.51 (1.75–7.01) | < 0.001 | 61 | 0.04 | Random |
| Invasion depth (T3–T4 vs. T1–T2) | 3 | 276 | 1.94 (1.36–2.75) | < 0.001 | 0 | 0.49 | Fixed |