Table 2. Differentially expressed genes between MH and MPM.
| UP REGULATED GENES IN MPM | DOWN REGULATED GENES IN MPM | ||||
|---|---|---|---|---|---|
| GENES | Z-VALUE | P-VALUE | GENES | Z-VALUE | P-VALUE |
| ITGB4 | -4.70564 | 0.000003 | LGALS3 | 4.79643 | 0.000002 |
| ITGA3 | -4.67538 | 0.000003 | PDGFRB | 4.61486 | 0.000004 |
| MCM4 | -4.52408 | 0.000006 | ITGAM | 4.37277 | 0.000012 |
| KRT5 | -4.46355 | 0.000008 | PECAM1 | 4.25172 | 0.000021 |
| NMU | -4.31461 | 0.000016 | CAV1 | 4.16094 | 0.000032 |
| FANCI | -4.22146 | 0.000024 | MMP9 | 3.97959 | 0.000069 |
| CCNB1 | -4.07016 | 0.000047 | NF2 | 3.82806 | 0.000129 |
| DSP | -3.70702 | 0.000210 | PAPPA | 3.70702 | 0.000210 |
| RAD21 | -3.64650 | 0.000266 | ITGA5 | 3.67676 | 0.000236 |
| CENPF | -3.58597 | 0.000336 | TACC1 | 3.67676 | 0.000236 |
| TOP2A | -3.55571 | 0.000377 | MYH11 | 3.49538 | 0.000473 |
| MCM2 | -3.52545 | 0.000423 | CD44 | 3.40440 | 0.000663 |
| PAK4 | -3.52545 | 0.000423 | PPARA | 3.28336 | 0.001026 |
| EGFR | -3.40440 | 0.000663 | ACSL1 | 3.13205 | 0.001736 |
| MSLN | -3.40440 | 0.000663 | TGFBR2 | 3.10179 | 0.001924 |
| CCNB2 | -3.34388 | 0.000826 | BAP1 | 3.07153 | 0.002130 |
| CLDN15 | -3.28336 | 0.001026 | VWF | 3.04143 | 0.002355 |
| CCNO | -3.25551 | 0.001132 | MMP1 | 3.02832 | 0.002459 |
| BIRC5 | -3.25328 | 0.001141 | FN1 | 2.70839 | 0.006761 |
| CDK7 | -3.16231 | 0.001565 | ITGA7 | 2.70839 | 0.006761 |
| CDH1 | -3.13222 | 0.001735 | ADCY4 | 2.67813 | 0.007404 |
| NME2 | -3.07153 | 0.002130 | MMP7 | 2.62642 | 0.008629 |
| LGALS3BP | -2.98075 | 0.002876 | COL1A1 | 2.58735 | 0.009672 |
| PKM | -2.92022 | 0.003498 | NOTCH1 | 2.52682 | 0.011510 |
| MKI67 | -2.85970 | 0.004241 | TPPP | 2.49930 | 0.012444 |
| BUB1 | -2.79918 | 0.005124 | JAG1 | 2.37552 | 0.017525 |
| PLK1 | -2.58735 | 0.009672 | DNMT1 | 2.13343 | 0.032890 |
| CDK1 | -2.55709 | 0.010556 | EGR3 | 2.13343 | 0.032890 |
| CXADR | -2.52682 | 0.011510 | EMX2 | 2.04893 | 0.040470 |
| AURKA | -2.49656 | 0.012541 | Gli1 | 2.03705 | 0.041646 |
| UBE2T | -2.43604 | 0.014850 | SOD1 | 2.01238 | 0.044181 |
| Gli2 | -2.40578 | 0.016139 | PTGS2 | 1.89134 | 0.058580 |
| LAMA3 | -2.31500 | 0.020614 | ESR2 | 1.81249 | 0.069911 |
| CHEK1 | -2.13343 | 0.032890 | SELE | 1.78203 | 0.074745 |
| NDC80 | -2.13343 | 0.032890 | JUNB | 1.52820 | 0.126464 |
| MICAL2 | -1.95186 | 0.050956 | COL16A1 | 1.37689 | 0.168546 |
| MMP3 | -1.93918 | 0.052480 | PTGIS | 1.31637 | 0.188051 |
| SMARCA4 | -1.92160 | 0.054657 | SDHB | 1.31637 | 0.188051 |
| ASS1 | -1.89134 | 0.058580 | EEF2 | 1.28611 | 0.198406 |
| GALNT7 | -1.83081 | 0.067129 | COL4A2 | 1.16506 | 0.243994 |
| MAGED1 | -1.83081 | 0.067129 | ITGA4 | 1.16506 | 0.243994 |
| PCNA | -1.83081 | 0.067129 | PIK3CA | 1.13480 | 0.256459 |
| EIF4G1 | -1.77029 | 0.076680 | MMP12 | 1.04605 | 0.295541 |
| CDH11 | -1.67951 | 0.093054 | SDC1 | 1.01376 | 0.310700 |
| MAD2L1 | -1.37689 | 0.168546 | BMP1 | 0.98349 | 0.325365 |
| HEG1 | -1.01376 | 0.310700 | TUBB2B | 0.89276 | 0.371987 |
| ADAMTS8 | -0.91104 | 0.362276 | TERT | 0.82029 | 0.412050 |
| PLK2 | -0.83219 | 0.405304 | CD274 | 0.77167 | 0.440313 |
| VEGFA | -0.71114 | 0.476997 | CDK4 | 0.77167 | 0.440313 |
| CTNNA1 | -0.62036 | 0.535022 | MMP14 | 0.77167 | 0.440313 |
| CFB | -0.59010 | 0.555126 | GNAQ | 0.74140 | 0.458449 |
| TIMP3 | -0.52957 | 0.596408 | THBS2 | 0.71114 | 0.476997 |
| TNPO2 | -0.43879 | 0.660814 | PDCD1 | 0.68092 | 0.495924 |
| IFITM1 | -0.40853 | 0.682886 | CDKN2B | 0.65062 | 0.515293 |
| MMP10 | -0.28336 | 0.776901 | SERPINE1 | 0.46905 | 0.639033 |
| DNMT3A | -0.25722 | 0.797008 | SFRP1 | 0.37827 | 0.705232 |
| XPOT | -0.25722 | 0.797008 | FGF2 | 0.28748 | 0.773743 |
| SULF1 | -0.13618 | 0.891682 | LAMC1 | 0.25722 | 0.797008 |
| CDKN2A | 0.09096 | 0.927526 | |||
Up and downregulated genes in MPM, reported according to the results of Mann-Whitney U-test.