Figure 2. Immunodepletion of CD147 suppresses the canonical NFκB signaling.

A. Representative images of western blot analysis of the canonical NFκB factors p105, p50 and p65 in CD147-immunodepleted testis and anti-CD147 treated GC-2 cells. The GC-2 cells were treated with 10 μg/mL anti-CD147 for 48 h. The testis was injected with 10μl mouse anti-CD147 mAb (40 μg/mL) and the total protein of testes was harvested after nine days. β-tubulin was used as the loading control. B. The corresponding statistical analysis (*, p<0.05 vs IgG control), the experiments were repeated 3 times. Values represent the mean±SEM.