Table 1. Baseline characteristics of the patients.
Characteristic (n = 15) | Median (range) or total number (%) | |
---|---|---|
Age | 73 | (54 - 81) |
ECOG | ||
0 | 5 | (33%) |
1 | 5 | (33%) |
2 | 5 | (33%) |
Gleason sum | ||
7 | 1 | (7%) |
8 | 1 | (7%) |
9-10 | 13 | (87%) |
Sites of metastases | ||
Bone | 14 | (93%) |
Lymph node | 12 | (80%) |
Liver | 3 | (20%) |
Other | 2 | (13%) |
Lung | 1 | (7%) |
Mean pain intensity score at baseline (0-10) | ||
0 | 5 | (33%) |
1-5 | 8 | (53%) |
6-10 | 2 | (13%) |
Biochemical values | ||
Lactate dehydrogenase (U/L) | 287 | (167 - 1220) |
Hemoglobin (g/dL) | 12.3 | (8.3 - 15.5) |
Total alkaline phosphatase (U/L) | 147 | (49 - 420) |
PSA (μg/L) | 388 | (3.2 - 10661) |
No. of prior hormonal therapies | ||
1 | 1 | (7%) |
2 | 4 | (27%) |
3 | 7 | (47%) |
≥4 | 3 | (20%) |
No. of prior chemotherapy regimens | ||
0 | 5 | (33%) |
1 | 5 | (33%) |
≥2 | 5 | (33%) |
Prior 223Ra | 5 | (33%) |
Prior EBRT | 9 | (60%) |
Abbreviations: ECOG, Eastern Cooperative Oncology Group Performance Status; EBRT, External Beam Radiation Therapy.