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. 2016 Sep 29;8(2):3666–3682. doi: 10.18632/oncotarget.12343

Table 2. Potential miRNAs as treatment targets for AML.

miRNA target genes or pathways References
miR-141 PI3K/Akt/mTOR [113]
miR-125a ErbB pathway [10]
miR-125b Mcl-1 [11, 12]
miR-22-3p, let-7e-5p PLK1 [114]
miR-34a PD-L1 [80]
miR-638 CDK2 [34]
miR-181a, b and c PRKCD, CTDSPL and CAMKK1 [6, 36, 96, 97]
miR-191-5p, miR-142-3p PPP2R2A [19, 115]
miR-181b MDR [36]
miR-21, miR-196b HOX [98]
miR-29a/b/c Dnmts [19, 22]