Table S.1.

The positive expression of PI3K, P70S6K1, ERK, and HIF-1α in paraffin embedded sections of rat lung. Compared with the negative group, *P<0.05.

DOSE (mg/kg)	N	PI3K			P70S6K1			ERK			HIF-1α
		+	–		+	–		+	–		+	–
0.00	15	0	15		0	15		0	15		0	15
0.50	15	3	12		2	13		5*	10*		0	15
1.00	15	6*	9*		7*	8*		8*	7*		2	13
2.00	15	11*	4*		11*	4*		11*	4*		10*	5*
3.00	15	15*	0*		15*	0*		15*	0*		15*	0*
nickel	15	15	0		15	0		15	0		15	0