Table 5a.

Univariate analysis of factors associated with VO2max in subjects with Fontan physiology

	Beta	95% CI	p
Habitual activity (per 10 hours/week)	6.0	−3.6 to 15.7	0.22
Age	−4.4	−6.3 to −2.5	<0.001
Male sex	−10.3	−22.3 to 1.78	0.09
Systemic ventricle
Right	1	n/a	n/a
Left	15.5	2.0 to 28.9	0.03
Both	21.7	−8.8 to 52.1	0.16
Restrictive atrial septum	−9.8	−48.0 to 28.2	0.61
Pulmonary vein anomaly	−10.2	−32.7 to 12.3	0.37
Heterotaxy	−13.6	−33.3 to 6.0	0.17
Stage 1 operation
Norwood with modified BTS	1	n/a	n/a
Norwood with RV to PA conduit	15.5	−11.5 to 42.6	0.26
Shunt without arch reconstruction	19.1	5.05 to 33.3	0.009
No operation	6.5	−11.8 to 24.7	0.40
Other	8.7	−43.5 to 61.0	0.74
Fontan operation
Extra-cardiac Fontan	1	n/a	n/a
Lateral tunnel Fontan	−12.7	−25.2 to −0.2	0.047
Hepatic vein inclusion	−23.2	−54.1 to 7.6	0.14
Protein losing enteropathy	−21.0	−45.2 to 3.1	0.09
Pacemaker	−4.2	−31.5 to 23.2	0.76
Exercise class
Low impact	1	n/a	n/a
Moderate impact	−7.8	−28.0 to 12.5	0.45
High impact	−6.7	−25.8 to 12.5	0.49
Restriction
No restriction	1	n/a	n/a
Moderate exertion	11.2	−2.9 to 25.4	0.12
Mild exertion	−4.5	−22.6 to 13.5	0.62
Transthoracic echocardiogram (n=69)
Systolic function
Normal	1	n/a	n/a
Mildly diminished	3.3	−13.7 to 20.2	0.70
Moderately diminished	−27.8	−48.2 to −7.4	0.008
Atrioventricular valve regurgitation
None to trivial	1	n/a	n/a
Mild	1.1	−10.0 to 12.2	0.84
Moderate	−13.3	−25.2 to −1.4	0.03
Severe	−53.5	−92.5 to −14.6	0.008
Cardiac MRI (n=8)
Ejection fraction	1.4	−1.2 to 4.1	0.24
Indexed stroke volume	0.5	−1.2 to 2.2	0.51
Cardiac index	5.4	−28.5 to 39.2	0.71