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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2016 Sep 17;173:69–74. doi: 10.1016/j.jsbmb.2016.09.015

Figure 2.

Figure 2

Agonistic properties of BXL0124 and BXL0097 in VDR-mediated transcription. Transient transfection assays with expression vectors encoding full-length VDR protein were performed in HEK293 EBNA cells in order to evaluate transcriptional activity of the receptor on the hCYP24A1 promoter controlling luciferase reporter gene in response to increasing amounts of tested compounds or vehicle. Normalized amount of the expressed luciferase is presented in relative light units (RLU) intensity. Data are presented as mean ± standard error of the mean.