Table 4.
Pearson Correlations of Demographic and Clinical Variables with Chemokine Index based on Eotaxin-1 and MDC Levels in Schizophrenia and Healthy Comparison Groups
| Schizophrenia | Healthy Comparison | |||
|---|---|---|---|---|
|
| ||||
| r or t | p | r or t | p | |
|
|
||||
| Age (years) | .23* | .007 | .11 | .24 |
| Gender | 1.1† | .26 | 2.1†* | .04 |
| Race | 1.8† | .07 | .23† | .82 |
| Education (years) | .14† | .89 | −.84† | .40 |
| Body mass index | −.16 | .06 | .05 | .60 |
| Current smoking status | −1.0† | .32 | −1.5† | .14 |
| Illness duration (years) | .21* | .02 | -- | -- |
| SAPS- total | .01 | .87 | -- | -- |
| SANS- total | .18* | .04 | -- | -- |
| Antipsychotic daily dosage (Total WHO DDD) | −.05 | .60 | -- | -- |
| Depressive symptoms (PHQ-9 severity score) | .01 | .95 | .28** | .003 |
| Psychotropic medication | −.28† | .78 | .1.3† | .20 |
| Anti-inflammatory medication | −.03† | .97 | −.66† | .51 |
| Multisystem Disease Risk score | .04 | .70 | .21 | .05 |
| SF-36, Physical Composite Scale | .01 | .90 | −.11 | .26 |
| SF-36, Mental Composite Scale | .01 | .87 | −.20* | .04 |
| CIRS- total score | .13 | .16 | .30** | .003 |
| CIRS- severity score | .04 | .66 | .26* | .01 |
| Executive Functioning Composite | −.11 | .20 | −.05 | .64 |
| Framingham Coronary Heart Disease Risk score | .04 | .68 | .16 | .10 |
r = Pearson’s correlation,
t = Student’s t, SAPS = Scale for the Assessment of Positive Symptoms, SANS = Scale for the Assessment of Negative Symptoms, WHO DDD = World Health Organization defined daily dose, PHQ = patient health questionnaire, SF-36 = Medical Outcome Survey 36-item Short Form, CIRS = Cumulative Illness Rating Scale;
significant difference at ≤ 0.01 and 0.05, respectively.