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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Kidney Int. 2016 Dec 18;91(4):896–913. doi: 10.1016/j.kint.2016.10.015

Figure 9. Schema of study findings.

Figure 9

Podocyte injury leads to increased ERK1/2 activation in PECs, which increases CD44 expression and causes matrix production and PEC migration to the glomerular tuft resulting in increased glomerular sclerosis.