Table 2.
Studies on margin status in TLM for early glottic carcinomas
| Tumor stage | First author (year published) | Number | Free margins defined as (mm) | Positive or inadequate margins (%) | Action on positive or inadequate margins |
|---|---|---|---|---|---|
| Tis–T1 | Hartl (2007) [68] | 79 | >2 | 32 | 9%: re-excision 91%: FU |
| Sigston (2006) [64] | 52 | >0.5 | 35 | 100%: FU | |
| Tis–T2 | Ansarin (2009) [72] | 274 | >1 | 34 | 38%: re-excision 30%: RT 32%: FU |
| Grant (2009) [69] | 49 | NA | 31 | 60%: re-excision 13%: RT 27%: FU |
|
| Mortuaire (2006) [65] | 110 | NA | 24 | 100%: FU | |
| Tis–T3 | Peretti (2010) [28] | 595 | >1 | 50 | 24%: re-excision 76%: FU |
| T1 | Michel (2011) [70] | 64 | >1–2 | 38 | 4%: re-excision 96%: FU |
| Manola (2008) [73] | 31 | >1–2 | 29 | 22%: re-excision 11%: RT 66%: FU |
|
| Brondbo (2007) [66] | 171 | >1–2 | 36 | 100%: FU | |
| T1–T2 | Fang (2013) [67] | 75 | >1–2 | 51 | 100%: FU |
| Crespo (2006) [71] | 40 | NA | 20 | 25%: RT 75%: FU |