Table 2.
Changes in biochemical parameters after nephrectomy
| Parameter | Baseline | After nephrectomy | p value |
|---|---|---|---|
| eGFR (ml/min/1.73 m2) | 87.3 ± 19.2 | 69.8 ± 24.7 | p < 0.001 |
| Creatinine (mg/dl)a | 0.82 (0.56–1.7) | 1.02 (0.58–6.28) | p < 0.001 |
| Calcium (mmol/l) | 2.31 ± 0.11 | 2.17 ± 0.15 | p < 0.001 |
| Phosphate (mmol/l) | 1.14 ± 0.2 | 0.97 ± 0.24 | p = 0.002 |
| iPTH (pmol/l) | 3.12 (2.02–3.66) | 2.68 (2.04–4.51) | p = 0.6 |
| Soluble Klotho (pg/ml) | 709.8 (599.9–831.2) | 583.0 (411.7–752.6) | p < 0.001 |
| c–FGF-23 (RU/ml) | 70.5 (49.8–103.3) | 77.1 (60.5–109.1) | p = 0.9 |
| CTX (ng/ml) | 0.49 (0.4–0.64) | 0.59 (0.46–0.85) | p = 0.001 |
| bALP (U/l) | 23.6 (18.8–31.4) | 17.9 (15.0–22.0) | p < 0.001 |
| TRAP 5b (U/l) | 3.3 (3.0–3.7) | 2.8 (2.3–3.2) | p < 0.001 |
| FECa (%) | 0.67 (0.33–0.85) | 1.14 (0.59–1.38) | p = 0.02 |
| TmPO4/eGFR (mmol/l) | 1.07 (0.84–1.35) | 0.8 (0.64–0.93) | p = 0.001 |
Data are presented as number (percentage), mean ± SD or median (interquartile range)
eGFR estimated glomerular filtration rate, iPTH intact parathyroid hormone, c-FGF-23 c-terminal fibroblast growth factor 23, CTX cross-linked C-telopeptide of type 1 collagen, bALP bone-specific alkaline phosphatase, TRAP 5b tartrate-resistant acid phosphatase 5b, FE Ca urinary fractional excretion of calcium, TmPO 4 /eGFR ratio of tubular maximum reabsorption rate to the glomerular filtration rate
aFor creatinine, data are presented as the median (min–max)