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. 2016 Oct 7;42(3):777–787. doi: 10.1007/s11064-016-2075-x

Fig. 3.

Fig. 3

Decreases in the content of the reduced glutathione (GSH) in primary CGC cultures challenged for 30 min with TBBPA. a The effects of different concentrations of TBBPA and vehicle (0.5 % DMSO) on the GSH content. b Modulation of the effects of 10 and 25 µM TBBPA by the free radical scavengers 1 mM reduced glutathione (GSH) and 10 µM butylated hydroxyanisole (BHA) dissolved in 0.1 ‰ ethanol (ET), and by the combination of RyR and NMDAR antagonists 2.5 µM bastadin 12 (bast), 200 µM ryanodine (ryan) and 0.5 µM MK-801 (MK). GSH content in CGC is presented as percent of control (the untreated cultures). The results are the mean values ± SD (n = 15). *Results significantly different from the control. #Results significantly different from the corresponding group treated only with TBBPA (p < 0.05)