Table 1.
Women with LS or first-degree relatives at 50% risk of the LS mutation | Symptomatic women | |||||
---|---|---|---|---|---|---|
First surveillance LS* (N = 52) | Second surveillance LS* (N = 33) | Third surveillance LS* (N = 17) | Fourth surveillance LS* (N = 5) | Fifth surveillance LS* (N = 3) | First visit (N = 50) | |
Mean age (range) | 45.1 (33–69) | 46.4 (34–70) | 46.2 (35–71) | 50.4 (40–66) | 53.2 (41–67) | 59.4 (40–82) |
Menopausal status | ||||||
Premenopausal | 40 (77 %) | 26 (79 %) | 13 (76 %) | 3 (60 %) | 2 (67 %) | 12 (24 %) |
Postmenopausal | 12 (23 %) | 7 (21 %) | 4 (24 %) | 2 (40 %) | 1 (33 %) | 38 (76 %) |
Number of children | ||||||
Nulliparous | 11 (21 %) | 8 (24 %) | 4 (24 %) | 1 (20 %) | 1 (33 %) | 2 (4 %) |
Primi/multiparous | 36 (69 %) | 21 (64 %) | 11 (65 %) | 3 (60 %) | 1 (33 %) | 33 (66 %) |
Unknown | 5 (10 %) | 4 (12 %) | 2 (11 %) | 1 (20 %) | 1 (33 %) | 15 (30 %) |
Started surveillance with endometrial sampling before the study period | 28 (54 %) | 21 (64 %) | 13 (76 %) | 5 (100 %) | 3 (100 %) | NA |
* First surveillance with endometrial sampling and VAS score, 28 (54%) women have had more surveillance visits with endometrial sampling before this study period