. Author manuscript; available in PMC: 2017 Mar 19.

Published in final edited form as: Int J Geriatr Psychiatry. 2010 Dec 9;26(6):593–601. doi: 10.1002/gps.2568

Table 3.

Characterization of depression and plasma Aβ1-40/1-42 ratio

Depressed subjects	High plasma Aβ1-40/ 1-42 ratio N = 23	Low plasma Aβ1-40/ 1-42 ratio N = 64	p-values
Age, year, Mean + SD	71.9 ±7.6	69.7±7.5	0.22
ApoE4, n/total (%)	7/23 (29%)	11/63(17%)	0.25
MCI, n/total (%)	16/23(67%)	23/64 (36%)	0.02
Amygdala volume, ml, mean±SD	3.3±0.8	3.8±0.8	0.04
Hippocampus volume, ml, mean±SD	5.0±0.7	5.1 ±0.9	0.88
Total brain volume, Liter, mean±SD	0.95 ±0.07	1.04±0.12	0.005

Depressed elderly subjects were used for the analysis and further divided into two subgroups according to plasma Aβ1-40/1-42 ratio. The Q4 (top 25%) of plasma Aβ1-40/1-42 ratio (>11.2) was used, as a high and the rest Q1-Q3 were used as a low levels of plasma Aβ1-40/1-42 ratio. Mean ± SD with t-test and n/ total (%) with chi-square were presented. p-values for statistical significance are shown.