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. Author manuscript; available in PMC: 2017 Mar 19.
Published in final edited form as: Int J Geriatr Psychiatry. 2010 Dec 9;26(6):593–601. doi: 10.1002/gps.2568

Table 3.

Characterization of depression and plasma Aβ1-40/1-42 ratio

Depressed subjects High plasma Aβ1-40/
1-42 ratio N = 23
Low plasma Aβ1-40/
1-42 ratio N = 64
p-values
Age, year, Mean + SD 71.9 ±7.6 69.7±7.5 0.22
ApoE4, n/total (%) 7/23 (29%) 11/63(17%) 0.25
MCI, n/total (%) 16/23(67%) 23/64 (36%) 0.02
Amygdala volume, ml, mean±SD 3.3±0.8 3.8±0.8 0.04
Hippocampus volume, ml, mean±SD 5.0±0.7 5.1 ±0.9 0.88
Total brain volume, Liter, mean±SD 0.95 ±0.07 1.04±0.12 0.005

Depressed elderly subjects were used for the analysis and further divided into two subgroups according to plasma Aβ1-40/1-42 ratio. The Q4 (top 25%) of plasma Aβ1-40/1-42 ratio (>11.2) was used, as a high and the rest Q1-Q3 were used as a low levels of plasma Aβ1-40/1-42 ratio. Mean ± SD with t-test and n/ total (%) with chi-square were presented. p-values for statistical significance are shown.