FIGURE 2.

Effects of ddC on endocannabinoid system molecules transcript levels in the brain, spinal cord and paw skin of female BALB/c mice. Relative mRNA expression of (A) endocannabinoid-synthesizing enzymes Napepld, Plcβ1, Daglα and Daglβ, (B) endocannabinoid-inactivating enzymes Faah and Mgll, and (C) cannabinoid receptors Cnr1 and Cnr2 in the brains, spinal cords, and paw skins of BALB/c mice on day 6 after administration of the ddC or its vehicle. Each bar represents the mean ± SEM of the values obtained from 6 to 10 vehicle-treated mice and 5–8 ddC-treated mice. ^∗p < 0.05, ^∗∗p < 0.01 compared to vehicle-treated mice (Student’s t-test).