Table 2.
Antibiotic susceptibility of P. aeruginosa wild-type and CDF-mutant strains.
Strain | MIC (μg/ml) | |||
---|---|---|---|---|
aCP | GM | CIP | IMI | |
PAO1 | 256 | 1 | 1 | 2 |
aitP::dTn5 | 256 | 1 | 1 | 2 |
czcD::dTn5 | 128 | 0.5 | 0.125 | 0.5 |
yiiP::dTn5 | 128 | 0.5 | 0.125 | 0.5 |
DM011b | 128 | 0.5 | 0.125 | 0.5 |
DM013 | 128 | 0.5 | 0.125 | 0.5 |
C-czcD | 256 | N.D.c | 1 | 2 |
C-yiiP | 256 | N.D. | 1 | 2 |
CP, chloramphenicol; GM, gentamicin; CIP, ciprofloxacin; IMI, imipenem.
In this nomenclature the first digit correspond to zntA gene, the second to pvdA gene and the third to CDF genes. Zero means no mutation of the gene while 1 indicates mutation of the gene. For CDFs, 1 means czcD mutation, and 3 means yiiP mutation.
N.D., not determined.