Fig. 2.

Vertex-wise comparison of cortical thickness in the patients with nasopharyngeal carcinoma in the before radiotherapy (pre-RT) group, the after radiotherapy (post-RT-ED) group of the early-delayed stage, and the after radiotherapy (post-RT-LD) group of the late-delayed stage in this study. The clusters correspond to the regions with statistically significant group difference in cortical thickness. In the calculations, we used Monte Carlo simulation, with a threshold of p < 0.05, to provide cluster-wise multiple-testing comparisons. The color bar indicates the significance level of group differences. Clusters in cold (warm) color indicate significantly decreased (increased) cortical thickness in the post-RT-ED (post-RT-LD) compared to pre-RT (pre-RT or post-RT-ED) group. Details of these clusters are listed in Table 2.