Fig. 4.

ROI-wise analysis of cortical thickness between the patients with nasopharyngeal carcinoma in the after radiotherapy (post-RT-ED) group of the early-delayed stage and the after radiotherapy (post-RT-LD) group of the late-delayed stage in this study. This analysis was based on each region of the Destrieux cortical atlas which parcellates each hemisphere into 74 ROIs. Specifically, 9 of the total 148 brain regions in warm color show significantly increased thickness in the post-RT-LD group compared to the post-RT-ED group. Details of cortical thickness for these ROIs are listed in Table 3. In summary, we found 24 ROIs showing significant between-group differences with the ROI-wise analysis. Bar plot of the average cortical thickness for each group in these ROIs are showed in Fig. 3, Fig. 4. The bars and error bars correspond to the average cortical thickness and the standard deviation in the given group. The horizontal cap lines with ‘**’ represent p-value < 0.01.