Table 1.
Demographic characteristics of the patients with nasopharyngeal carcinoma in the before radiotherapy (pre-RT) group, the after radiotherapy (post-RT-ED) group of the early-delayed stage, and the after radiotherapy (post-RT-LD) group of the late-delayed stage in this study. One-way analysis of variance (ANOVA) with Bonferroni post hoc tests was performed to assess differences in age, Karnofsky performance status (KPS) score, and total intracranial volume. And a χ2-test was used to assess the differences in gender composition, AJCC stage among the three groups, and treatment protocol, chemotherapy between the post-RT-ED and post-RT-LD group (p < 0.05, two-sided). Abbreviations: N/A, not applicable; AJCC, American Joint Committee on Cancer; 2D–CRT, conventional two-dimensional radiotherapy; IMRT, intensity-modulated radiation therapy.
| Characteristics | Pre-RT | Post-RT-ED | Post-RT-LD | p-Value |
|---|---|---|---|---|
| Age (years old) | 44.09 ± 9.54 | 48.59 ± 5.96 | 45.45 ± 9.91 | 0.22 |
| Gender (female/male) | 5/17 | 3/19 | 5/15 | 0.62 |
| Total intracranial volume (cm3) | 1437.32 ± 131.33 | 1477.81 ± 157.38 | 1480.48 ± 143.44 | 0.55 |
| Karnofsky performance status (KPS) score | 87.05 ± 3.72 | 86.77 ± 2.71 | 86.90 ± 2.92 | 0.96 |
| Period between RT and imaging (months) | N/A | 3.32 ± 1.59 | 10.90 ± 1.68 | |
| Chemotherapy (with/without) | N/A | 21/1 | 19/1 | 0.95 |
| Treatment protocol (2D–CRT/IMRT) | N/A | 18/4 | 13/7 | 0.22 |
| AJCC stage (I/II/III/IV) | 1/4/12/5 | 1/8/9/4 | 1/5/9/5 | 0.91 |