Table 1.
Characteristics of WHO EC trials using LNG
| Trial | EC regimen used in trial | Participating centres in countries | Number of LNG cases included in this analyses (sample size) |
|---|---|---|---|
| A. Hong Kong 1993 [4] A prospective randomized comparison of LNG with Yuzpe regimen; Delay 0–48 h | Two LNG 0.75-mg doses with 12-h interval | 1 centre in Hong Kong | 410 (440) |
| B. WHO 1998 [5] RCT of LNG versus Yuzpe regimen; Delay 0–72 h | Two LNG 0.75-mg doses with 12-h interval | 21 centres in 14 countries | 974 (1001) |
| C. WHO 2002 [6] Low-dose mifepristone and two regimens of LNG; Delay 0–120 h | One LNG 1.5 mg dose Two LNG 0.75-mg doses with 12-h interval | 15 centres in 10 countries | 2695 (2756) |
| D. Nigeria 2010 [7] A randomized double-blind study to compare two regimens of LNG; Delay 0–120 h | One LNG 1.5 mg dose Two LNG 0.75-mg doses with 12-h interval | 7 centres in Nigeria | 2794 (3022) |
| Total pooled data | One LNG 1.5 mg dose Two LNG 0.75-mg doses with 12-h interval | 31 centres in 17 countries | 6873 (7219) |