Table 1.
Clinicopathological features of the entire cohort
| Variable | MMR-proficient (n = 44) | MMR-deficient (n = 17) | χ2 | p-value |
|---|---|---|---|---|
| Age at diagnosis (yr) | 54 (31–78) | 55 (41–74) | - | .58a |
| Size (cm) | 5.1 (1.8–11.0) | 6.1 (1.8–15.0) | - | .14a |
| Sex | 0.897 | .34b | ||
| Male | 31 | 14 | ||
| Female | 13 | 3 | ||
| Anatomic location | 0.002 | .96b | ||
| Right | 8 | 3 | ||
| Left | 36 | 14 | ||
| T stage | 2.074 | .36b | ||
| T1 | 0 | 0 | ||
| T2 | 4 | 0 | ||
| T3 | 39 | 16 | ||
| T4 | 1 | 1 | ||
| Differentiation | 3.498 | .32b | ||
| Well | 12 | 3 | ||
| Moderate | 31 | 13 | ||
| Poor | 1 | 0 | ||
| Mucinous | 0 | 1 | ||
| Lymph node metastasis | 2.273 | .13b | ||
| No | 19 | 11 | ||
| Yes | 25 | 6 | ||
| Lymphovascular space invasion | 0.123 | .75b | ||
| No | 33 | 12 | ||
| Yes | 11 | 5 | ||
| Perineural invasion | 1.082 | .30b | ||
| No | 37 | 16 | ||
| Yes | 7 | 1 | ||
| CEA at diagnosis (ng/mL) | 37.1 (0.2–1,042.8) | 63.4 (1.1–852.5) | - | .49a |
| Metastastic site | ||||
| Liver | 21 | 15 | ||
| Lung | 23 | 2 |
Values are presented as mean (range) or number.
MMR, mismatch repair; CEA, carcinoembryonic antigen.
a
Mann-Whitney test;
b
Fisher exact or χ2 tests.