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Mouse Fcγ receptors (FcγRs). Schematic illustration of mouse receptors for IgG. FcγRs are shown relative to the cell membrane (yellow line) and together with their respective signaling subunits. γ2, FcR gamma subunit dimer; β2m, beta-2 microglobulin; ITAM, immunoreceptor tyrosine-based activation motif (green rectangle); ITIM, immunoreceptor tyrosine-based inhibition motif (red rectangle); FcRn, neonatal Fc receptor. TRIM21 is a cytosolic receptor.
