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. 2017 Mar 20;7:44706. doi: 10.1038/srep44706

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Typical transmission electron microscopy images of serum exosomes isolated from healthy controls (Normal), from Kawasaki disease patients (KD), and from Kawasaki disease patients after intravenous immunoglobulin treatment (+IVIG). (B) Statistics regarding vesicle diameters for the three sample types in (A), measured based on the transmission electron microscopy images. For each type of sample, 200 vesicles were measured. (C) Western blot of exosome protein markers (CD9, CD81, and TSG101) in total serum and isolated exosomes. Equal amounts of protein were loaded in each lane.