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. 2017 Mar 20;15:58. doi: 10.1186/s12916-017-0821-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Forest plot of trial primary outcomes organized by statistically significant testing and if potentially clinical meaningful effects are indicated by the point estimates (≤0.94) and/or the confidence intervals (≤0.75). RCT randomized controlled trial. * Not statistically significant as p-value adjusted for multiple comparisons