Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 6;4(23):e13056. doi: 10.14814/phy2.13056

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Tgfbr1 ^iko femoral arteries (FAs) produce higher levels of MMP9 than do Tgfbr1 ^f/f FAs in the adventitial layer at the advanced stage. (A) Immunofluorescence staining of MMP2 and MMP9 in FAs with indicated genotype on d28. An uninjured Tgfbr1 ^f/f FA was included as a reference for the baseline levels of these proteins. Positive staining of these proteins appears in green. Negative controls omitting the primary antibodies are shown on the far right. White dashed lines delineate EEL. Scale bars, 50 μm. Levels of MMP2 (B) and MMP9 (C) in myointimal and adventitial layers of the indicated FAs (n = 7 per genotype). Data were expressed as intensity of the staining (arbitrary unit, AU) normalized to the corresponding region. *P = 0.039 (C), t‐test.