Figure 3. The percentage change of absolute concentration for major synovial FAs prior- and post-DMM surgery.

Surgery significantly decreased the absolute concentrations of most lipid species in synovial fluid in the operated joints. In general, ω-6 mice tended to have larger changes in the absolute concentration of synovial fluid FAs post-surgery, while ω-3 mice appeared to have less alterations in lipid composition of synovial fluid. One-way ANOVA with Tukey’s post-hoc was performed to evaluate the effect of diet on each lipid concentration. Different letters are significantly different from each other (p < 0.05).