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. 2017 Mar 20;7:44765. doi: 10.1038/srep44765

Figure 2. Classification of disease/infection groups.

Figure 2

Time series kinetics of CFU shedding, IFN-γ and ELISA assay expressions for each of the 57 cattle grouped into separate categories based on immune and shedding patterns. Group 1 is classified as silent infections. In this group no shedding is observed and immune responses are not distinct and differently expressed. In Group 2 (sub-clinical infections), intermittent shedding is observed, while IFN-γ and ELISA test show differential expression of immune responses. Animals with high consistent CFU shedding and high IFN-γ and ELISA are categorized as Group 3, and are assumed to be in the clinical state.