Table 1. Enrichment of NF-κB binding sites in genes repressed by PML-RARα identified by Martens et al. 13.
| Factor | JASPAR ID | z-score | Fisher score |
|---|---|---|---|
| NF-κB binding sites enriched in genes upregulated by ATRA treatment of NB4 cells | |||
| NFKB | MA0105.1 | 65.870 | 25.600 |
| NF-KappaB | MA0061.1 | 54.991 | 11.949 |
| REL | MA0101.1 | 36.077 | 7.155 |
| RELA | MA0107.1 | 35.260 | 8.094 |
| NF-κB binding sites enriched in genes bound by PML-RARα. | |||
| NF-KappaB | MA0061.1 | 24.512 | 38.293 |
| NFKB1 | MA0105.1 | 22.585 | 32.796 |
| REL | MA0101.1 | 20.515 | 32.875 |
| RELA | MA0107.1 | 17.850 | 24.352 |
JASPR ID refers to the matrix model in the JASPAR CORE database. Sites with a z-score >10 or a Fisher score of >7 are considered significantly enriched26.