Table 1.
Total | Prostate cancer (+) | Prostate cancer (−) | P | |
---|---|---|---|---|
No. of patients | 421 | 100 (23.8) | 321 (76.2) | |
Age at initial PBx (yr) | 66.1 ± 8.1 | 67.9 ± 7.3 | 65.5 ± 8.29 | 0.009 |
PSA at initial PBx (ng/mL) | 8.90 ± 7.13 | 8.46 ± 6.51 | 9.04 ± 7.32 | 0.533 |
PSA at repeat PBx (ng/mL) | 10.01 ± 8.77 | 10.67 ± 10.13 | 9.80 ± 8.31 | 0.426 |
Prostate volume (cc) | 47.62 ± 22.94 | 38.16 ± 16.32 | 50.66 ± 23.94 | < 0.001 |
PSA density at initial PBx (ng/mL/cc) | 0.20 ± 0.14 | 0.24 ± 0.18 | 0.19 ± 0.12 | 0.024 |
PSA density at repeat PBx (ng/mL/cc) | 0.23 ± 0.23 | 0.29 ± 0.24 | 0.22 ± 0.17 | 0.016 |
No. of PBx core (n) | 13.34 ± 4.42 | 14.24 ± 5.18 | 13.06 ± 0.41 | 0.039 |
No. of PSA down at the first follow up after initial PBx | 106 (25.2) | 29 (29.0) | 77 (24.0) | 0.849 |
Levels of PSA down at the first follow up after initial PBx (ng/mL) | 0.15 ± 0.91 | −1.58 ± 9.05 | 0.68 ± 9.07 | 0.073 |
PSAV before the initial PBx (ng/mL/yr) | 0.56 ± 27.15 | 2.88 ± 15.31 | −0.06 ± 29.55 | 0.619 |
PSAV before the repeat PBx (ng/mL/yr) | 0.31 ± 25.68 | −3.17 ± 48.52 | 1.41 ± 11.28 | 0.461 |
PSAV between the initial and repeat PBx (ng/mL/yr) | 4.51 ± 34.94 | 8.93 ± 44.78 | 3.11 ± 31.21 | 0.258 |
Average of PSA levels before the initial PBx (ng/mL) | 8.76 ± 7.38 | 8.65 ± 7.94 | 8.80 ± 7.21 | 0.875 |
Standard deviation of PSA levels before the initial PBx (ng/mL) | 3.20 ± 6.53 | 1.85 ± 3.23 | 3.66 ± 7.25 | 0.008 |
Average of PSA levels for the follow-up duration (ng/mL) | 9.26 ± 6.75 | 9.37 ± 7.41 | 9.22 ± 6.54 | 0.866 |
Standard deviation of PSA levels for the follow-up duration (ng/mL) | 2.73 ± 4.31 | 2.52 ± 4.47 | 2.79 ± 4.26 | 0.656 |
Average of PSA levels after the repeat PBx (ng/mL) | 7.29 ± 6.55 | 7.29 ± 6.55 | 0.812 | |
Standard deviation of PSA levels after the repeat PBx (ng/mL) | 2.93 ± 6.32 | 2.93 ± 6.32 | 0.842 |
Data are presented as n (%) or mean ± SD.
PBx, prostate biopsy; PSA, prostate cancer-specific antigen; PSAV, PSA velocity.