Table 5.
In the matched cohort, the association between each biomarker and the risk of all-cause CV events in the GN and non-GN groups using multivariable models that included interaction terms between the GN vs non-GN group and each biomarker
| Biomarker | HR | 95% CI | |
|---|---|---|---|
| uACR (per log unit) | GN | 1.02 | 0.81–1.30 |
| Non-GN | 1.30 | 1.03–1.62 | |
| ADMA (per 1StD) | GN | 1.54 | 0.95–2.50 |
| Non-GN | 1.06 | 0.82–1.37 | |
| ProBNP (per 1StD) | GN | 2.21 | 1.43–3.40 |
| Non-GN | 2.54 | 1.68–3.86 | |
| CRP (per 1StD) | GN | 1.70 | 1.11–2.60 |
| Non-GN | 1.22 | 0.81–1.84 | |
| IL6 (per 1StD) | GN | 1.57 | 1.12–2.22 |
| Non-GN | 1.43 | 0.95–2.16 | |
| Troponin I (>LLD vs. <LLD) |
GN | 3.57 | 1.55–8.22 |
| Non-GN | 12.16 | 4.64–31.87 |
uACR, ProBNP, CRP and IL6 were log-transformed for analysis
Abbreviations: LLD lower limit of detection, StD standard deviation