Table 1. Demographic and Pretest Values for Treatment and Control Groups.
Variable | Allopurinol Group (n = 12) | Placebo Group (n = 12) | P-value |
---|---|---|---|
Gender, n (%) | 0.667 | ||
Females | 3 (25.0) | 7 (58.3) | |
Males | 9 (75.0) | 5 (41.7) | |
Age, y (SD) | 59.2 (10.1) | 62.4 (9.5) | 0.307 |
Ethnicity, n (%) | 0.197 | ||
African American | 4 (33.3) | 8 (66.7) | |
Caucasian | 4 (33.3) | 1 (8.3) | |
Hispanic | 4 (33.3) | 3 (25.0) | |
Weight (kg), mean (SD) | 86.31 (14.10) | 88.35 (31.54) | 0.138 |
Systolic BP, mean (SD) | 142.17 (14.30) | 139.25 (30.07) | 0.764 |
Diastolic BP, mean (SD) | 76.17 (9.97) | 73.67 (15.92) | 0.649 |
GFR, mean (SD) | 47.30 (15.90) | 45.10 (19.80) | 0.503 |
Diabetes, n (%) | 8 (66.7) | 5 (41.7) | 0.154 |
CRP, mean (SD) | 7.73 (2.06) | 8.87 (3.18) | 0.717 |
IL-6, mean (SD) | 21.76 (14.43) | 17.38 (12.46) | 0.327 |
TNF-α, mean (SD) | 22.10 (9.91) | 23.33 (11.76) | 0.703 |
Albumin, mean (SD) | 4.24 (0.24) | 4.11 (0.43) | 0.445 |
CRP, uric acid, and albumin are measured in mg/dL; IL-6, IL-1β, and TNF-α are measured in pg/mL.