Table 1. Baseline Characteristics According to Degree of Ischemia (n = 503).
Mild ischemia n = 230 (46%) | Mod /Sev ischemia n = 273 (54%) | P | |
---|---|---|---|
Mean age (years) (SD) | 69 (± 11) | 68 (± 11) | 0.18 |
Age > 65 years | 148 (64%) | 165 (60%) | 0.41 |
Male gender | 182 (79%) | 215 (79%) | 1.00 |
Hypertension | 198 (86%) | 225 (82%) | 0.27 |
Hyperlipidemia | 187 (81%) | 212 (78%) | 0.19 |
Diabetes | 79 (34%) | 85 (31%) | 0.45 |
History of smoking | 131 (57%) | 168 (62%) | 0.32 |
Previous MI | 93 (40%) | 113 (41%) | 0.86 |
Previous CVA | 31 (13%) | 25 (9%) | 0.15 |
Previous TIA | 8 (3%) | 8 (3%) | 0.80 |
PVD | 39 (17%) | 56 (21%) | 0.36 |
Chronic renal failure | 19 (8%) | 31 (11%) | 0.30 |
Mean creatinine (SD) | 1.3 mg/dL (± 0.8 mg/dL) | 1.3 mg/dL (± 0.7 mg/dL) | 0.87 |
Dialysis | 5 (2%) | 2 (1%) | 0.26 |
Atrial fibrillation/flutter | 47 (20%) | 39 (14%) | 0.07 |
Prior revascularization | 109 (47%) | 110 (40%) | 0.13 |
Aspirin | 175 (76%) | 205 (75%) | 0.75 |
Clopidogrel | 49 (21%) | 51 (19%) | 0.50 |
Warfarin | 33 (14%) | 20 (7%) | 0.01 |
Betablocker | 157 (68%) | 177 (65%) | 0.39 |
ACE inh/ARB | 125 (54%) | 142 (52%) | 0.59 |
Statin | 160 (70%) | 181 (66%) | 0.44 |
Diuretic (loop or thiazide) | 70 (30%) | 86 (32%) | 0.85 |
Aldosterone antagonist | 6 (3%) | 6 (2%) | 0.78 |
Calcium channel blocker | 44 (19%) | 61 (22%) | 0.44 |
Digoxin | 16 (7%) | 10 (4%) | 0.11 |
Echo | |||
EF (mean, SD) | 58% (14) | 58% (13) | 0.78 |
EF > 50% | 168 (73%) | 201 (74%) | 0.68 |
WMA | 115 (50%) | 127 (47%) | 0.47 |
≤ 3 segments | 25 (11%) | 21 (9%) | 0.33 |
≤ 6 segments | 37 (16%) | 46 (17%) | 0.59 |
> 6 segments | 36 (16%) | 42 (15%) | 0.78 |
Diffusely hypokinetic | 17 (7%) | 18 (7%) | 1.00 |
Nuclear | |||
Summed Rest Score | 16 (± 9) | 12 (± 7) | < 0.001 |
Summed Stress Score | 19 (± 9) | 18 (± 7) | 0.53 |
Summed Difference Score | 3 (± 3) | 7 (± 4) | < 0.001 |
Revascularization | 79 (34%) | 167 (61%) | < 0.001 |
Death | 31 (13%) | 33 (12%) | 0.69 |