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Binding affinity: inhibition curves of [3H]PIB-labeled Aβ plaques in postmortem human brain hippocampal homogenate by TAZA and PIB (average of two measurements). The measured IC50 values were TAZA= 1.28 nM and PIB =10 nM and calculated Ki values were TAZA= 0.84 nM and PIB= 6.67 nM.
