Fig. S12.

Human myelin disperses widely and integrates very well among endogenous myelin in adult mice. (A) Serial coronal sections of the grafted adult Shi/Shi Rag2^−/− mouse spinal cord stained for MOG (red) and MBP (green) reveal MOG⁺/MBP⁻ endogenous and MOG⁺/MBP⁺ exogenous myelin, respectively, and illustrates the widespread distribution of human-derived MBP⁺ myelin along the rostro-caudal axis (between 10 and 22 mm in length) 12 wpg. (B) Illustration of more caudal sections expressing MOG only (internal negative controls). n = 3 mice. (Scale bar, 1,000 µm.)